In quotes provided Wednesday by Harpo Productions, Osmond says it was a "calculated decision" for her to return to work within weeks of her son's death because the "stage is my safe place."
Osmond says she "knew that if I didn't get back on stage that I may never get back on stage."
The episode of "The Oprah Winfrey Show" will air Thursday.
Osmond's son, 18-year-old college student Michael Bryan, jumped from the eighth floor of an apartment building in Los Angeles in February. The coroner ruled the death suicide.
Osmond and her brother, Donny, took a brief break from their Las Vegas show before returning with a teary tribute to Bryan in March.